120.0K
XNAS Volume
High volume today
XNAS 04 Apr, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Mar 2025 | 1,026,228 | 1,896,609 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 31 Jan 2025 | 2,470,355 | 870,381 | - | - | Convertible Loan Agreement | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 20 Jun 2024 | 37,500 | 37,500 | - | - | Director Stock Option | ||
| Donald MacAdam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 37,500 | 37,500 | - | - | Director Stock Option | |
| Jan-Paul Waldin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 37,500 | 37,500 | - | - | Director Stock Option | |
| Peter Libby | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2024 | 37,500 | 37,500 | - | - | Director Stock Option | |
| Simard John | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Jan 2024 | 2,470,355 | 3,840,736 | - | - | Convertible Loan Agreement | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 23 Jun 2023 | 25,000 | 25,000 | - | - | Director Stock Option | ||
| Donald MacAdam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 25,000 | 25,000 | - | - | Director Stock Option | |
| Jan-Paul Waldin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 25,000 | 25,000 | - | - | Director Stock Option | |
| Peter Libby | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 25,000 | 25,000 | - | - | Director Stock Option | |
| Sushma Shivaswamy | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Feb 2023 | 100,000 | 100,000 | - | - | Employee Stock Option (right to buy) | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 22 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option | ||
| Donald MacAdam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option | |
| Jan-Paul Waldin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option | |
| Peter Libby | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2022 | 25,000 | 25,000 | - | - | Director Stock option | |
| Queena Han | VP Finance & HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2021 | 35,000 | 35,000 | - | - | Stock Option | |
| Sushma Shivaswamy | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Nov 2021 | 100,000 | 100,000 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.45 per share. | 07 Oct 2021 | 39,286 | 3,923,166 (13%) | 0% | 12.5 | 489,111 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.90 per share. | 07 Oct 2021 | 21,125 | 3,873,166 (13%) | 0% | 12.9 | 272,523 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.83 per share. | 07 Oct 2021 | 10,875 | 3,962,452 (13%) | 0% | 12.8 | 139,526 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.77 per share. | 07 Oct 2021 | 18,000 | 3,973,166 (14%) | 0% | 12.8 | 229,939 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.66 per share. | 04 Oct 2021 | 14,218 | 3,973,166 (14%) | 0% | 12.7 | 180,058 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 12.53 per share. | 04 Oct 2021 | 10,714 | 3,962,452 (13%) | 0% | 12.5 | 134,259 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 13.08 per share. | 04 Oct 2021 | 23,681 | 3,987,384 (14%) | 0% | 13.1 | 309,864 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 13.41 per share. | 28 Sep 2021 | 16,396 | 4,049,307 (14%) | 0% | 13.4 | 219,801 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 13.23 per share. | 28 Sep 2021 | 19,684 | 4,011,065 (14%) | 0% | 13.2 | 260,488 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 13.07 per share. | 28 Sep 2021 | 18,558 | 4,030,749 (14%) | 0% | 13.1 | 242,464 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 14.27 per share. | 28 Sep 2021 | 6,263 | 4,065,703 (14%) | 0% | 14.3 | 89,364 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 14.68 per share. | 23 Sep 2021 | 9,892 | 4,113,274 (14%) | 0% | 14.7 | 145,220 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 14.81 per share. | 23 Sep 2021 | 29,890 | 4,071,966 (14%) | 0% | 14.8 | 442,790 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 14.49 per share. | 23 Sep 2021 | 11,418 | 4,101,856 (14%) | 0% | 14.5 | 165,409 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 15.24 per share. | 20 Sep 2021 | 16,860 | 4,142,835 (14%) | 0% | 15.2 | 256,913 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 15.06 per share. | 20 Sep 2021 | 13,471 | 4,159,695 (14%) | 0% | 15.1 | 202,914 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 15.14 per share. | 20 Sep 2021 | 19,669 | 4,123,166 (14%) | 0% | 15.1 | 297,757 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 18.15 per share. | 14 Jul 2021 | 50,000 | 4,173,166 (14%) | 0% | 18.1 | 907,350 | Common Stock |
| Donald MacAdam | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.40 per share. | 09 Jul 2021 | 10,000 | 10,000 (0%) | 0% | 4.4 | 44,000 | Common Shares |
| Donald MacAdam | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Jul 2021 | 10,000 | 2,500 | - | - | Stock options | |
| Peter Libby | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Jul 2021 | 25,000 | 0 | - | - | Stock options | |
| Peter Libby | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.76 per share. | 09 Jul 2021 | 25,000 | 25,000 (0%) | 0% | 7.8 | 194,000 | Common Shares |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 22 Jun 2021 | 25,000 | 25,000 | - | - | Stock Option | ||
| Donald MacAdam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2021 | 25,000 | 25,000 | - | - | Stock Option | |
| Jan-Paul Waldin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2021 | 25,000 | 25,000 | - | - | Stock Option | |
| Peter Libby | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2021 | 25,000 | 25,000 | - | - | Director Stock option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2021 | 500,000 | 0 | - | - | Stock options | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.50 per share. | 22 Mar 2021 | 500,000 | 4,223,166 (14%) | 1% | 7.5 | 3,750,000 | Common Shares |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | 28 Jan 2021 | 13,484 | 61,516 | - | - | Stock Options | ||
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | 28 Jan 2021 | 500,000 | 500,000 | - | - | Stock Options | ||
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | 28 Jan 2021 | 150,000 | 150,000 | - | - | Stock Options | ||
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | 28 Jan 2021 | 89,260 | 110,740 | - | - | Stock Options | ||
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | 28 Jan 2021 | 1,875 | 48,125 | - | - | Stock Options | ||
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 19 Nov 2020 | 375,000 | 2,560,964 (9%) | 1% | 18.3 | 6,862,500 | Common Stock | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 18 Sep 2020 | 500,000 | 3,723,166 (13%) | 1% | - | Common Stock | |
| Sushma Shivaswamy | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Sep 2020 | 20,668 | 0 | - | - | Stock Options | |
| Sushma Shivaswamy | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Sep 2020 | 19,332 | 0 | - | - | Stock options | |
| Sushma Shivaswamy | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 10 Sep 2020 | 20,668 | 0 (0%) | 0% | 20 | 413,360 | Common Shares |
| Sushma Shivaswamy | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.50 per share. | 10 Sep 2020 | 20,668 | 20,668 (0%) | 0% | 7.5 | 155,010 | Common Shares |
| Sushma Shivaswamy | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.50 per share. | 10 Sep 2020 | 19,332 | 19,332 (0%) | 0% | 7.5 | 144,990 | Common Shares |
| Sushma Shivaswamy | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.01 per share. | 10 Sep 2020 | 19,332 | 0 (0%) | 0% | 20.0 | 386,833 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.24 per share. | 01 Sep 2020 | 30,000 | 30,000 (0%) | 0% | 4.2 | 127,200 | Common Stock |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2020 | 27,692 | 0 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2020 | 30,000 | 0 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.16 per share. | 01 Sep 2020 | 27,692 | 57,692 (0%) | 0% | 4.2 | 115,199 | Common Stock |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 27 Aug 2020 | 25,000 | 25,000 | - | - | Stock Option | ||
| Donald MacAdam | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2020 | 25,000 | 25,000 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2020 | 25,000 | 25,000 | - | - | Stock Option | |
| Jan-Paul Waldin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Aug 2020 | 25,000 | 25,000 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 19.65 per share. | 24 Aug 2020 | 12,500 | 0 (0%) | 0% | 19.7 | 245,679 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.50 per share. | 24 Aug 2020 | 18,700 | 18,700 (0%) | 0% | 7.5 | 140,250 | Common Shares |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 19.65 per share. | 24 Aug 2020 | 18,700 | 0 (0%) | 0% | 19.7 | 367,535 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.00 per share. | 24 Aug 2020 | 5,000 | 5,000 (0%) | 0% | 15 | 75,000 | Common Shares |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 19.65 per share. | 24 Aug 2020 | 5,000 | 0 (0%) | 0% | 19.7 | 98,272 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.16 per share. | 24 Aug 2020 | 12,308 | 12,308 (0%) | 0% | 4.2 | 51,201 | Common Shares |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 19.65 per share. | 24 Aug 2020 | 12,308 | 0 (0%) | 0% | 19.7 | 241,905 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.14 per share. | 24 Aug 2020 | 3,333 | 3,333 (0%) | 0% | 4.1 | 13,799 | Common Shares |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 19.65 per share. | 24 Aug 2020 | 3,333 | 0 (0%) | 0% | 19.7 | 65,508 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.26 per share. | 24 Aug 2020 | 12,500 | 12,500 (0%) | 0% | 5.3 | 65,750 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2020 | 18,700 | 0 | - | - | Stock options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2020 | 5,000 | 0 | - | - | Stock Options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2020 | 12,308 | 0 | - | - | Stock Options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2020 | 3,333 | 0 | - | - | Stock Options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2020 | 12,500 | 0 | - | - | Stock Options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.50 per share. | 17 Aug 2020 | 1,300 | 1,300 (0%) | 0% | 7.5 | 9,750 | Common Shares |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Aug 2020 | 1,300 | 0 | - | - | Stock options | |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 19.30 per share. | 17 Aug 2020 | 1,300 | 0 (0%) | 0% | 19.3 | 25,090 | Common Stock |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 12 Feb 2020 | 1,462,636 | 2,935,964 (10%) | 5% | 30 | 43,879,080 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 12 Feb 2020 | 15,874 | 31,864 (0%) | 0% | 30 | 476,220 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 12 Feb 2020 | 33,252 | 66,748 (0%) | 0% | 30 | 997,560 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 12 Feb 2020 | 3,825 | 7,676 (0%) | 0% | 30 | 114,750 | Common Stock | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Sale or transfer of securities back to the company at price $ 30.00 per share. | 12 Feb 2020 | 2,103,894 | 4,223,166 (14%) | 7% | 30 | 63,116,820 | Common Stock |
| Jan-Paul Waldin | Director | Sale or transfer of securities back to the company at price $ 30.00 per share. | 12 Feb 2020 | 99,757 | 200,243 (0%) | 0% | 30 | 2,992,710 | Common Stock |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 06 Jan 2020 | 46,000 | 1,199,500 | - | - | Stock Option | ||
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 06 Jan 2020 | 77,000 | 1,245,500 | - | - | Stock Option | ||
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 06 Jan 2020 | 123,000 | 3,706,600 (13%) | 0% | 3.8 | 461,250 | Common Stock | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Dec 2019 | 1,000,000 | 2,625,000 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 29 Nov 2019 | 185,000 | 3,583,600 (12%) | 0% | 3.8 | 693,750 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 29 Nov 2019 | 185,000 | 0 | - | - | Stock Option | ||
| Queena Han | VP Finance & HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Nov 2019 | 75,000 | 75,000 | - | - | Stock Option | |
| Sushma Shivaswamy | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Nov 2019 | 100,000 | 100,000 | - | - | Stock Option | |
| Peter Libby | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jul 2019 | 25,000 | 25,000 | - | - | Director Stock option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 27 Jun 2019 | 25,000 | 25,000 | - | - | Stock Option | ||
| Donald MacAdam | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2019 | 25,000 | 25,000 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jun 2019 | 300,000 | 300,000 | - | - | Stock Option | |
| Jan-Paul Waldin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jun 2019 | 25,000 | 25,000 | - | - | Stock Option | |
| Sushma Shivaswamy | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2019 | 4,500 | 0 | - | - | Stock options | |
| Sushma Shivaswamy | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 10.00 per share. | 07 Feb 2019 | 4,500 | 0 (0%) | 0% | 10 | 45,000 | Common Stock |
| Sushma Shivaswamy | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.50 per share. | 07 Feb 2019 | 4,500 | 4,500 (0%) | 0% | 2.5 | 11,250 | Common Stock |
| Queena Han | VP Finance & HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2019 | 25,000 | 25,000 | - | - | Stock Option | |
| Sushma Shivaswamy | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2019 | 15,000 | 15,000 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 24 Dec 2018 | 18,636 | 46,374 (0%) | 0% | 5.1 | 94,567 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 24 Dec 2018 | 1,364 | 47,738 (0%) | 0% | 4.9 | 6,706 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 24 Dec 2018 | 24,838 | 27,738 (0%) | 0% | 5.9 | 146,097 | Common Stock | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.50 per share. | 19 Dec 2018 | 50,000 | 6,327,060 (17%) | 0% | 2.5 | 125,000 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Dec 2018 | 50,000 | 0 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 09 Nov 2018 | 700 | 2,900 (0%) | 0% | 3.8 | 2,625 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 09 Nov 2018 | 2,200 | 2,200 (0%) | 0% | 3.7 | 8,217 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 04 Oct 2018 | 385,000 | 3,398,600 (9%) | 1% | 3 | 1,155,000 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 26 Sep 2018 | 17,634 | 3,783,600 (10%) | 0% | 3.1 | 53,798 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 12 Sep 2018 | 41,675 | 3,809,143 (10%) | 0% | 3.1 | 127,546 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 12 Sep 2018 | 7,909 | 3,801,234 (10%) | 0% | 3.1 | 24,549 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 07 Sep 2018 | 23,369 | 3,850,818 (10%) | 0% | 3.2 | 75,335 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 07 Sep 2018 | 6,234 | 3,874,187 (10%) | 0% | 3.7 | 22,763 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 04 Sep 2018 | 7,220 | 3,887,580 (10%) | 0% | 3.9 | 28,481 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 04 Sep 2018 | 7,159 | 3,880,421 (9%) | 0% | 3.7 | 26,397 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 04 Sep 2018 | 3,800 | 3,894,800 (10%) | 0% | 4.0 | 15,179 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 09 Aug 2018 | 6,638 | 3,171 (0%) | 0% | 4.0 | 26,523 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 09 Aug 2018 | 3,171 | 0 (0%) | 0% | 4.0 | 12,623 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 06 Aug 2018 | 3,340 | 133,761 (0%) | 0% | 4.0 | 13,328 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 06 Aug 2018 | 8,452 | 125,309 (0%) | 0% | 3.9 | 33,332 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 06 Aug 2018 | 4,000 | 121,309 (0%) | 0% | 4.0 | 16,024 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 01 Aug 2018 | 8,163 | 79,962 (0%) | 0% | 4.2 | 34,649 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 01 Aug 2018 | 23,900 | 25,601 (0%) | 0% | 4.0 | 94,689 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 01 Aug 2018 | 30,461 | 49,501 (0%) | 0% | 3.9 | 119,529 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 30 Jul 2018 | 5,344 | 94,656 (0%) | 0% | 4.4 | 23,542 | Common Stock | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 30 Jul 2018 | 6,531 | 88,125 (0%) | 0% | 4.5 | 29,320 | Common Stock | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jul 2018 | 15,000 | 15,000 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 19 Jun 2018 | 25,000 | 25,000 | - | - | Stock Option | ||
| Donald MacAdam | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 12,500 | 12,500 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 200,000 | 200,000 | - | - | Stock Option | |
| Jan-Paul Waldin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2018 | 12,500 | 12,500 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2018 | 40,000 | 40,000 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2018 | 8,201 | 0 | - | - | Stock options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2018 | 62,200 | 0 | - | - | Stock options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2018 | 9,599 | 0 | - | - | Stock options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.50 per share. | 21 Mar 2018 | 9,599 | 9,599 (0%) | 0% | 2.5 | 23,998 | Common Stock |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 4.75 per share. | 21 Mar 2018 | 8,201 | 0 (0%) | 0% | 4.8 | 38,955 | Common Stock |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.50 per share. | 21 Mar 2018 | 8,201 | 8,201 (0%) | 0% | 2.5 | 20,503 | Common Stock |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 4.76 per share. | 21 Mar 2018 | 62,200 | 0 (0%) | 0% | 4.8 | 296,159 | Common Stock |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.50 per share. | 21 Mar 2018 | 62,200 | 62,200 (0%) | 0% | 2.5 | 155,500 | Common Stock |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 4.48 per share. | 21 Mar 2018 | 9,599 | 0 (0%) | 0% | 4.5 | 42,987 | Common Stock |
| Donald MacAdam | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Mar 2018 | 25,000 | 25,000 | - | - | Director Stock Option | |
| Jan-Paul Waldin | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2018 | 25,000 | 25,000 | - | - | Director Stock Option | |
| Sushma Shivaswamy | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2017 | 150,000 | 150,000 | - | - | Stock Option | |
| Benjamin Guzman | Sr.VP Corp. Strategy & Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jul 2017 | 300,000 | 300,000 | - | - | Employee Stock Option | |
| Daniel L Vasella | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 19 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option | ||
| Fabrizio Bonanni | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2017 | 30,000 | 50,000 | - | - | Stock Option | |
| Sushma Shivaswamy | VP Research and Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2017 | 75,000 | 75,000 | - | - | Stock Option | |
| Michael Stecher | Medical Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jun 2017 | 50,000 | 50,000 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.17 per share. | 24 May 2017 | 116,207 | 6,277,060 (17%) | 0% | 8.2 | 949,411 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.93 per share. | 24 May 2017 | 240,000 | 6,393,267 (18%) | 0% | 0.9 | 223,608 | Common Stock |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 May 2017 | 240,000 | 0 | - | - | Stock Option | |
| Daniel Vasella | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2016 | 23,867 | 23,867 | - | - | Stock Option | |
| Daniel Vasella | None | Sale or transfer of securities back to the company at price $ 0.00 per share. | 01 Dec 2016 | 125,000 | 0 | - | - | Stock Option | |
| Daniel Vasella | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Dec 2016 | 125,000 | 125,000 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Nov 2016 | 19,573 | 0 | - | - | Stock options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Nov 2016 | 19,573 | 19,573 | - | - | Common Shares | |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 15 Nov 2016 | 19,573 | 0 | - | - | Common Stock | |
| Fabrizio Bonanni | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2016 | 50,000 | 50,000 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 14 Sep 2016 | 50,000 | 50,000 | - | - | Stock Option | ||
| Daniel Vasella | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Sep 2016 | 50,000 | 50,000 | - | - | Stock Option | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Sep 2016 | 427 | 19,573 | - | - | Stock options | |
| Queena Han | VP Finance & HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Sep 2016 | 427 | 427 | - | - | Common Shares | |
| Queena Han | VP Finance & HR | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 08 Sep 2016 | 427 | 0 | - | - | Common Stock | |
| Trey Benson | VP of Commercial Development | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2016 | 8,000 | 8,000 | - | - | Stock options | |
| Kalidip Choudhury | VP of Business Development | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Aug 2016 | 50,000 | 50,000 | - | - | Stock options | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 20 May 2016 | 750 | 5,750 | - | - | Common Stock | ||
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 20 May 2016 | 750 | 5,750 | - | - | Common Stock | ||
| Dawn McCollough | VP Clinical Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2016 | 50,000 | 50,000 | - | - | Stock Options | |
| Scott Whitehurst | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 May 2016 | 300,000 | 300,000 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 17 Mar 2016 | 500,000 | 0 | - | - | Stock Option | ||
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 17 Mar 2016 | 500,000 | 3,898,600 | - | - | Common Shares | ||
| John Simard | Director, Ten Percent Owner | 17 Mar 2016 | 500,000 | 0 | - | - | Option to sell | ||
| John Simard | Director, Ten Percent Owner | 17 Mar 2016 | 500,000 | 6,153,267 | - | - | Common Shares | ||
| Fabrizio Bonanni | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2016 | 33,333 | 33,333 | - | - | Stock Option | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 01 Mar 2016 | 15,000 | 15,000 | - | - | Stock Option | ||
| Daniel Vasella | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2016 | 125,000 | 125,000 | - | - | Stock Option | |
| John Simard | Director, Chief Executive Officer, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2016 | 50,000 | 50,000 | - | - | Stock Option | |
| Queena Han | VP Finance / HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 40,000 | - | - | Stock Option | |
| Queena Han | VP Finance / HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 30,000 | - | - | Stock Option | |
| Queena Han | VP Finance / HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 20,000 | - | - | Stock Option | |
| Queena Han | VP Finance / HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 10,000 | - | - | Common Shares | |
| Queena Han | VP Finance / HR | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Dec 2015 | 7,700 | 2,300 | - | - | Common Shares | |
| Queena Han | VP Finance / HR | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Dec 2015 | 2,300 | 0 | - | - | Common Shares | |
| Queena Han | VP Finance / HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 10,000 | - | - | Common Shares | |
| Queena Han | VP Finance / HR | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Dec 2015 | 7,110 | 2,890 | - | - | Common Shares | |
| Queena Han | VP Finance / HR | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Dec 2015 | 2,890 | 0 | - | - | Common Shares | |
| Queena Han | VP Finance / HR | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 10,000 | - | - | Common Shares | |
| Queena Han | VP Finance / HR | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Dec 2015 | 10,000 | 0 | - | - | Common Shares | |
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 25 Nov 2015 | 18,400 | 3,398,600 | - | - | Common Shares | ||
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 25 Nov 2015 | 5,000 | 5,000 | - | - | Common Shares | ||
| W. Thorpe Mckenzie | Director, Ten Percent Owner | 25 Nov 2015 | 5,000 | 5,000 | - | - | Common Shares | ||
| Michael Stecher | Medical Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2015 | 1,800 | 58,200 | - | - | Stock Option | |
| Michael Stecher | Medical Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Nov 2015 | 1,800 | 1,800 | - | - | Common Shares | |
| Michael Stecher | Medical Director | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 16 Nov 2015 | 1,800 | 0 | - | - | Common Shares | |
| Kelly Thornburg | SVP of Operations | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jun 2015 | 70,368 | 70,368 | - | - | Employee Stock Option (Right to Buy) |